Love and Other Drugs is brash and manic and sexy, then grim and weepy and self-consciously inspirational. It's madly uneven. But it's also one of the few romantic movies in the past few years with strong and insightful satirical undertones. It's set in 1996, which wasn't quite the dawn of our psychopharmacological era — though it was certainly the morning — and Big Pharma sales-dude Jamie Randall, played by Jake Gyllenhaal, is an early riser. He's a supple, smooth-faced, blue-eyed cutie whom women fall for even when they know that his ingenuousness is an act: It's more winning than other men's genuine ingenuousness.Note that the movie is based on the nonfiction book, Hard Sell. Check the full NPR Fresh Air feature out here. Download the podcast here. See also: Hard Sell: Now a Major Motion Picture LOVE & OTHER DRUGS
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