Epigenetics arise! | Gene Expression from Discover Blog by Razib Khan

If Mike Lynch and Jerry Coyne have fits over Sean B. Carroll’s love affair with gene regulation at the expense of old fashion sequence variation, I wonder how they’ll view the inflation of epigenetics which is liable to get more out of control before people begin to gain a sense of perspective. I see on Amazon there are already some suspect titles trying to use epigenetics as stepping stones. For example, Happiness Genes: Unlock the Positive Potential Hidden in Your DNA. One of the blurbs [...]

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Drawing the Map of Life: Inside the Human Genome Project from Forum Network | Book Tour Podcast Podcast

Science writer and founder the Knight Science Journalism Fellowships at MIT, Victor McElheny, for a look into the workings of the Human Genome Project and his new book, Drawing the Map of Life. Drawing the Map of Life is the dramatic story of the Human Genome Project from its origins, through the race to order the three billion subunits of DNA, to the surprises emerging as scientists seek to exploit the molecule of heredity. It's the first account to deal in depth with the intellectual roots of the project, the motivations that drove it, and the hype that often masked genuine triumphs. Victor McElheny offers profiles of key people, such as David Botstein, Eric Lander, Francis Collins, James Watson, Michael Hunkapiller, and Craig Venter. McElheny also shows that the Human Genome Project is a striking example of how new techniques (such as restriction enzymes and sequencing methods) often arrive first, shaping the questions scientists then ask. Drawing on years of original interviews and reporting in the inner circles of biological science, Drawing the Map of Life is the definitive, up-to-date story of today's greatest scientific quest.

Download the podcast here. This is what Salon.com had to say about the book:

But these days, the popular excitement surrounding the project has largely abated: The sequencing of the genome hasn't led to the rollout of any game-changing new drugs; we've yet to discover the genes responsible for Alzheimer's or Huntington's, among many other diseases, and the era of mass personalized medicine — in which doctors can tailor treatments to people's specific genetic code — has yet to come. But as Victor McElheny, a longtime science reporter and the founder of the Knight Science Journalism Fellowship at MIT, points out in his new book about the tumultuous evolution of the Human Genome Project, "Drawing the Map of Life," the widespread impact of genome sequencing is only now beginning to be felt, and a new era of genetically informed medicine is just around the corner.

Read the full Salon.com piece here. See also: Genome: The Autobiography of a Species in 23 Chapters (P.S.), A Short Guide to the Human Genome, Inside the Human Genome: A Case for Non-Intelligent Design, The Genome War: How Craig Venter Tried to Capture the Code of Life and Save the World

Thomas Goetz - The Decision Tree from IT Conversations - Tech Nation Podcast

Dr. Moira Gunn and David Ewing Duncan talk personalized medicine with Wired magazine Executive Editor, Thomas Goetz.

Download the podcast here. See also: The Healing of America: A Global Quest for Better, Cheaper, and Fairer Health Care, Landmark: The Inside Story of America's New Health Care Law and What It Means for Us All (Publicaffairs Reports), Who Killed Health Care?: America's $2 Trillion Medical Problem - and the Consumer-Driven Cure